WELCOME: Four (3) semester hours, three hours lecture per week. Insights into DNA, RNA and proteins along with medical and ecological applications. Topics covered include: the history of discoveries in macromolecules, detailed macromolecular structures, protein folding, macromolecular interactions and mechanisms, eDNA, metagenomics, proteomics, proteins in environmental and medical studies, multi-omics approaches to disease and environmental studies.
PARTICIPATION: Students are expected to take part in discussion after or during lecture.
EXAMS: there will be two noncumulative exams for the first and the second part of the course. Context will include any material covered during lectures and oral presentations.
Course Requirements:
• Comprehensive Examinations: There will be two noncumulative exams for the first and the second part of the course. Context will include any material covered during lectures and labs. These exams will be of an objective or subjective format or combinations of both. These two lecture exams are worth 80 points each.
• Lecture Quizzes: Before each lecture there will be a short quiz which will cover the material learned since the previous quiz (required and recommended reading of materials available on-line). These quizzes will be a combination of multiple choice, matching, short answer. These lecture quizzes are worth 10 points each.
• Discussion Participation: Students are expected to participate in weekly discussions on the assigned readings. To facilitate discussion, each student is required to bring in five typed questions that they will submit each class. The grade will be determined based on the frequency of their participation as well as thoughtfulness/utility of their contributions to class discussion. This is worth 10 points.
Graduate Independent project: graduate students (only) will conduct an independent lab-based research project in which they gather data, analyze it, and present their findings in a written paper following the standard scientific format (Abstract, Introduction, Materials and Methods, Results, and Discussion). The project will be worth of 50 points (written portion 20 points, presenting 30 points)
• Other assignments: as described at the beginning of the semester and required by the Professor.

Program Learning Outcomes (PLO): The course is designed to address the following Program Learning Outcomes, as given in the M.S. Program in the Department of Biology:
PLO #1. The student will demonstrate a good knowledge base in biological concepts
Student Learning Outcomes (SLO):
1. Students will demonstrate thorough understanding of the structure and function of DNA, RNA and proteins at all levels with the emphases on their importance for medical and ecological studies. (PLO 1)
2. Students will demonstrate competency in experimental design and performance in lab research project including big data collection and big data analysis. (PLO 1)
3. Students will master independent and critical thinking skills integrated with the ability to utilize multiple informational resources. (PLO 1)
4. Students will master research skills in reviewing literature, developing an experimental design, working independently with laboratory equipment, troubleshooting, obtaining, and utilizing meaningful data, and formulating conclusions from their research results. (PLO 1)

ATTENDANCE: You are expected to attend all lectures according to the schedule– attendance will be monitored. Sign in with your full first name and last name as listed on the class roster. Students who do not provide their full name will be marked as absent. Missing classes without university approved absences will result in points subtraction from your Final grade. In contrast perfect attendance will give you extra points to your Final grade. Stay focused: turn off your cellphone and pack it away, be respectful to your classmates and professor. Students will benefit greatly by attending the class. It will be some discussions that are not included in the lec slides or/and schedule. Missing an exam/deadlines will be permitted only by prior arrangement and make-ups will only be allowed in the case of a University approved absence (illness with a doctor's note, a family crisis, or a religious holiday).
MATERIALS: PowerPoint presentations for each lecture will be online, according to the provided schedule of the course, so that handwritten notes can be made and used during the exam. REMEMBER: draw it to know it! I recommend to use GOOGLE CHROME to browse this page. Textbook is optional for this course: Biochemistry, by Donald Voet latest version.
GRADING CRITERIA:
Quizzes/independent activities - 10 pts
Midterm & Final EXAMS - 2X40 pts
Discussion Participation - 10 pts
Independant research project for GS - 50 pts
TOTAL - 100/150 pts
No SI
T 11-15, 19-20, or by appointment @S236
week meeting schedule topic activities lecture slides lecture video
2
1/17-20
T: Class Face-to-face meeting Meeting with the class.
3
1/23-27
T: Class Face-to-face meeting History of Discoveries in Molecular Biology
4
1/30-2/3
T: Class Face-to-face meeting Review - Nucleotides as a building blocks for nucleic acids.
DNA/RNA and it's primary structure
5
2/6-10
T: Class Face-to-face meeting DNA/RNA structure and function.
6
2/13-17
T: Class Face-to-face meeting DNA/RNA as multi-omics approaches to disease
7
2/20-24
T: Class Face-to-face meeting DNA/RNA tools for ecological research (Soil Biota)
eDNA and metagenomics.
8
2/27-3/3
T: Midterm (D2L) (nucleic acids part) First part: Midterm on d2l - multiple choice
9
3/6-10
Spring Break!!!!🏖️
10
3/13-17
T: Class Face-to-face meeting Protein’s low-level structure and function.
11
3/20-24
T: Class Face-to-face meeting Protein’s high-level structure and function
12
3/27-31
T: Class Face-to-face meeting Protein folding.
13
4/3-5
T: Class Face-to-face meeting
🐣 🐇 EASTER!
DNA, RNA /protein interactions.
Proteins - approaches to disease
14
4/10-14
T: Class Face-to-face meeting Lab exersize
15
4/17-21
T: Class Face-to-face meeting Proteins in environmental studies.
16
4/24-28
T: Class Face-to-face meeting Presentations/Independent projects
17
5/2
T: Final Exam (D2L)
Final is May 2nd at 17:00 at d2l
over an e-mail avankley@sfasu.edu (please do not email through D2L if you would like to get a quick reply). When emailing please indicate BOTH class & section # and your CID. When attaching a file, filename should be “First_LastName.ext”, it must also include your name in the document itself. Emails lacking any of the information listed above WILL BE IGNORED. Note: NO emails will be answered after 5 p.m. and/or during weekends. NO GRADE DISCUSSION over an e-mail, only by one on one meetings. Grades cannot be discussed via e-mail at any time due to federal law. I will speak to you in person instead during my office hours. DO NOT involve a third-party who is not affiliated in an official capacity with SFASU (e.g., friend, roommate) in any matters pertaining to your enrollment in this course. Your instructor is legally prohibited from discussing most course/grade-related issues with third parties according to the Family Educational Rights and Privacy Act (FERPA) (20 U.S.C. § 1232g; 34 CFR Part 99).
Address
1901 Raguet Street N, Miller Science Building, Room 101
Nacogdoches, TX 75962